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Study Protocol

Exploring the Age-Friendly Health Systems Framework in Memory Care Centres: A protocol for a mixed-methods study

[version 1; peer review: 2 approved with reservations]
PUBLISHED 06 Apr 2026
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This article is included in the Ageing Populations collection.

Abstract

Introduction

Age-Friendly Health Systems (AFHS) have demonstrated improved outcomes for older adults. However, there is currently no evidence that explores the implementation process of AFHS in long-term residential care settings. The overall aim of this study is to explore the implementation process of an Age-Friendly Health System for older adults in Mowlams’ Memory Care Centres in Ireland.

Methods

The conceptual framework for an AFHS designed by Karami et al. (2023) will be employed to delineate the dimensions of the AFHS within the Mowlam Memory Care residential centres. This framework defines an AFHS as being made up of eight core dimensions including governance, resources, service delivery, intermediate objectives, goals, stakeholders, information and an age friendly environment. This study will map activities to this framework using a mixed-methods. Older adults who are residents in one of the two Mowlam Memory Care residential centres; older residents’ families and those important to them; staff members at each Memory Care residential centre will be eligible for inclusion. Focus groups and one-to-one interviews will be performed with participants from each stakeholder group. Findings will be reported in accordance with the consolidated criteria for reporting qualitative research (COREQ) checklist. Qualitative data will be analysed thematically. Over a period of eight months, a prospective cohort study will be conducted to investigate clinical and patient-reported outcomes, as well as the various elements of care received by older adult residents in the Memory Care centres. Descriptive statistics will be employed to characterise the study participants, while multivariate logistic and linear regression analyses will be utilised to evaluate the risk of adverse outcomes.

Ethics and dissemination

Ethical approval for this study was granted. Findings will be submitted for publication in a peer-reviewed journal and disseminated in the form of presentations at national and international conferences.

Keywords

Age-Friendly Health Systems, 4Ms, memory care centre, residential care, long-term care

Introduction

Current demographic trends indicate that almost one in six adults in the European region will be aged 60 years and older by 2050, with one in four being of the ‘oldest old’ aged 85 years or over by 2040.1 The World Health Organization (WHO) recognises dementia as a public health priority.2 In 2021, 57 million people were living with dementia worldwide, with almost 90% of cases being older adults aged 65 years or more.2 Approximately 64,000 people are living with dementia in Ireland, and this number is expected to rise to 150,000 by 2045.3 In 2019, dementia cost the global economy an estimated US$1.3 trillion.2 In Ireland, annual dementia care expenditure exceeds €1.69 billion, with residential care accounting for 43% of this total.4 The demographic shift underscores the urgent need for specialised, evidence-based models of care that address the complex needs of older adults living with memory-related conditions in the community settings.

The Age-Friendly Health Systems (AFHS) 4Ms framework is an evidence-based model of care that originated in the United States, a collaborative of the John A. Hartford Foundation, Institute for Healthcare Improvement (IHI), and is designed to address the complex and multifaceted needs of older people.4,5 The AFHS 4Ms framework attempts to ensure that every older adult receives the highest quality care, is not harmed by care and is satisfied with the care they receive.6 It is a model of care that addresses the four key areas of an older adult’s health and wellbeing known as the 4Ms: What Matters, which emphasises aligning care with an older adults individual preferences; Medication, which should be regularly evaluated for their risks and benefits, ensuring they do not conflict with the other Ms; Mentation, which involves identifying and managing conditions such as dementia, depression, and delirium; and Mobility, which aims to sustain physical function and independence.4 The 4Ms framework enables healthcare providers to provide more effective and integrated healthcare and focuses on “what matters” to each older adult by considering all aspects of an older adult’s health and wellbeing.6

The requirement for long term residential care (LTRC) for older persons is expected to double over the next 15 years.7 It is estimated that approximately 64% of people living with dementia in Ireland live at home, and 72% of residents in residential care are living with dementia.8 Mowlam Healthcare is Ireland’s second largest provider of LTRC for older persons.9 It employs approx. 2,000 staff and has a similar number of residents in 35 care centres, including specific Memory Care residential centres. Although evidence suggests improved outcomes for older adults who receive age-friendly health care based on the 4Ms framework, including reduced incidence of delirium, Mate et al. (2021) called for future research to explore the implementation of the AFHS 4Ms framework across teams and to understand the 4Ms set as an intervention that can be used to rigorously examine and measure the outcomes of 4Ms and care.4 While the AFHS concept has been proposed for more than a decade, the methods and extent of its of its implementation, as well as the outcomes achieved, remain unclear. To the best of our knowledge, this is the first study to explore the implementation of AFHS in memory care residential centres internationally.

The overall aim of this study is to explore the implementation process of an AFHS for older adults in Mowlams’ Memory Care Centres in Ireland. A mixed-methods approach will be adopted including:

  • 1) Focus groups and interviews with stakeholders including Memory Care Centre residents and their families, HSCPs and management staff to explore the process of implementation of an AFHS approach, and to

  • 2) Characterise the profile of Memory Care Centre residents who receive age-friendly healthcare and the elements and processes of care they receive in relation to the 4Ms framework over an 8-month period, through conduct of a prospective cohort study.

This information will be used to inform a foundational understanding of the AFHS 4Ms model of care in Memory Care Centres in Ireland and inform the future implementation of AFHS policy, practice and research.

Methods

Study design

This study will involve a mixed-methods approach. Focus groups and one-to-one interviews will be performed with participants from each stakeholder group (including Memory Care Centre residents and their families, HSCPs and management staff ). The focus groups will be moderated by the research team (CH, RG, IO’S) using a prepared semi-structured interview guide. The qualitative study will adhere to the Consolidated Criteria for Reporting Qualitative Research (COREQ) guidelines.10 This study will be guided the 4Ms Framework of AFHS.4,5

The profile of Memory Care residents, process, clinical and patient-reported outcomes related to the 4Ms framework will be captured over an 8-month period. Description of elements of age-friendly healthcare received and initiatives for implementation carried out by staff of will be recorded through the conduct of a prospective cohort study. The STROBE standardised reporting guidelines will be followed in the conduct and reporting of this study.11 Participant data collection and follow-up will occur between February 2026 and October 2026 (inclusive). This study has been submitted for registration on clinicaltrials.gov registry.

Ethics

Ethical approval for this study was received from the Education and Health Sciences (EHS) Research Ethics Committee at the University of Limerick (2025_11_11_EHS). Written informed consent will be obtained from eligible participants, in accordance with the Data Protection Act 2018 (Section 36(2).12

Setting

The study setting will be across two Mowlam Memory Care residential centres; Cloverlodge, Kildare and Adare, Limerick. All care homes share a similar population with residents having high levels of dependency and complexity. Most residents are from the local community and are admitted when they are unable to independent care of themselves as a result of medical illness. Residents have a variety of dependency needs that typically require full time nursing care in order to fulfil daily activities. Both Adare and Kildare care for a mix of long-term care and residents living with dementia. All homes are predominantly staffed with a combination of Registered Nurses and Healthcare Assistants overseen by Clinical Nurse Managers, Assistant Directors of Nursing and a Director of Nursing. This is supported by a Regional Healthcare Manager and a Quality and Compliance Co-ordinator. A dedicated Health and Social Care Professional (physiotherapist) is allocated to the care centre based on bed capacity with others available as required (dietetics, OT) and each centre has a visiting General Practitioner. Finally, care centres are linked to specialist community services as part of an integrated care agenda. This includes Integrated Care Programme, Older Persons (ICPOP), Palliative care or Psychiatry of Later Life.

Name of centreNumber of beds (maximum capacity)
Adare78
Cloverlodge60

Population of interest

Mowlam staff at various levels and fulfilling various functions. Older adults aged ≥65 years who are resident in one of the two Mowlam Memory Care residential centres; those important to residents; staff members at each Mowlam Memory Care residential centre; and Mowlam management staff who consent to participate will be eligible to participate in the interviews/focus groups.

Older adults aged ≥65 years who reside in one of the two Mowlam Memory Care residential centres and provide consent to participate will be deemed eligible for recruitment in the prospective cohort study.

Exclusions to recruitment will apply where older adults or staff decline to consent or LTRC residents with limited capacity or change of condition.

Exposure

Mowlam has introduced the 4Ms in each of the three care centres. This includes revision of documentation, care planning and process changes and dedicated staff education. Alterations were introduced to the electronic health record to include mandatory assessments that capture the 4Ms as well as changes to the Care Plan structure and process. The daily safety pause now includes the 4Ms to reinforce its use in practice and links the daily care to individual care plans. Each care centre has introduced AFHS champions and hold regular meetings to monitor implementation. Each centre introducing the 4Ms have collaborated with stakeholders including families and residents, producing posters on the 4Ms that provide information as well as individualised 4 M templates in each resident’s room that captures What Matters to Them. A suite of educational modules has been introduced that are available through the Mowlam Academy for all staff. Finally, regular three-monthly audits capture the application of 4Ms for each resident as a matter of Mowlam’s audit cycle.

Baseline data collection

Anonymous data will be extracted from Mowlam’s central database. Baseline data collection will include participant’s age, sex, ethnicity, marital status, length of residential status, socioeconomic status and education level. In addition to demographic data collection, health information including mobility status (DEMMI, TUG, FRASE), falls incidence in the previous six months, medications, history of dementia diagnosis (MMSE), pain (Numeric Rating Scale (0–10), Wong Baker Scale and FLACC), hygiene and comfort (oral health, wound care, falls, pain, continence, swallow), emotional well-being (HAD, Geriatric Depression Scale), advanced care planning (end of life).

Follow-up data collection

Qualitative interviews and focus groups will be conducted at four months post baseline data collection. An interview guide will be prepared in advance to guide open-ended questioning on key areas of interest around the AFHS 4Ms framework. All interviews will be audio recorded, anonymised to ensure confidentiality and transcribed verbatim and checked by the research team for accuracy.

All data will be retrieved from Mowlam’s database by an independent member of the research team (CH) at four and eight months. The number of primary and secondary healthcare use including emergency department (ED) presentations, hospitalisations, General Practitioner visits will be ascertained from Mowlam’s database. Withdrawals and participants lost to follow-up will be recorded.

Health information including mobility status mobility status (DEMMI, TUG, FRASE), falls incidence in the previous four months, medications, history of dementia diagnosis (MMSE), pain (Numeric Rating Scale (0–10), Wong Baker Scale and FLACC), mortality, hygiene and comfort (oral health, wound care, falls, pain, continence, swallow), emotional well-being (HAD, Geriatric Depression Scale), safety incidents, resource use, advanced care planning (end of life).

Outcome variables

The primary outcome of this study is stakeholder experiences of the implementation process of an AFHS for older adults in Mowlam Memory Care residential centres in Ireland.

Secondary outcomes include mobility, falls, medications, dementia, pain, mortality, hygiene and comfort, QoL, safety incidents, AFHS initiatives used, staff joy at work and level of training completed by staff.

Sample size

It is expected that that approximately ten participants from each stakeholder group (Memory Care residential centre residents/families and staff ) will participate in either one-to-one interviews or focus groups, depending on participant preference.

This prospective cohort study will not be hypothesis driven; therefore, formal power calculations will not apply. All older adults that meet inclusion criteria will be invited to participate during the study recruitment period (January 2026– April 2026 inclusive).

Data analysis

Overarching framework

The conceptual framework for an AFHS designed by Karami et al. (2023) will be employed to profile the dimensions of the AFHS within the Mowlam Memory Care centres ( Table 1).13 This framework defines an AFHS as being made up of eight core dimensions including governance, resources, service delivery, intermediate objectives, goals, stakeholders, information and an Age Friendly environment. Karami and colleague’s framework highlights specific features of each dimension required for an AFHS to realise its goals.13 This study will systematically map activities within Mowlam’s Memory Care residential centres to this framework and will include both a qualitative and quantitative component.

Table 1. Conceptual framework of age-friendly health system.13

GovernanceResourcesService deliveryIntermediate objectivesGoalsPopulation (stakeholders)InformationAn age-friendly environment

  • Incorporation of older adults’ needs in line with the 4Ms framework

  • Increasing awareness and promotion of AFHS

  • Active involvement of older adults’ participation in health and policy at all levels

  • Providing opportunities for engagement for residents, their families and caregivers in shared decision-making

  • Availability of speciality AFHS training

  • Provision of a user-friendly environment for providing services tailored to residents

  • Access to appropriate medical equipment, access to care and safety of medicines

  • Provision/access to evidence-based care and services to ensure coordinated provision of person-centred care

  • Provision of and access to evidence-based care for older people, enhancing the quality of care for older adults, and enabling better selfcare and health outcomes

  • Promotion of health ageing

  • Maintenance of functional ability and well-being for older adults

  • Non-governmental input such as families, volunteers and educational groups

  • Needs assessment and comprehensive approach to care

  • Research and development, monitoring and evaluation, and documentation to inform practice and improve performance

  • Provision of an age-friendly environment physically and psychologically through mobility and social activities

Qualitative data analysis will involve verbatim transcription of focus groups and interviews conducted by members of the research team. The transcripts will be stored in a password-protected online database. Reflexive thematic analysis will be performed following Braun and Clarke’s six-step approach; familiarisation; coding; generating initial themes; reviewing and developing themes; refining, defining and naming themes; and writing up.14,15 NVIVO (Version 15) software will be utilised for qualitative analysis.

Anonymised data will be securely stored in a password-protected online database, while hard copies of consent forms and follow-up questionnaires will be kept in a locked cabinet in an office with restricted access. Descriptive statistics will be employed to profile the baseline characteristics of the cohort. Categorical data (e.g. biological sex) will be analysed using frequencies and percentages, whereas continuous data (e.g. age) will be analysed using means and standard deviations (SD) or median and interquartile ranges (IQR) where data demonstrates evidence of skewness. One-way within-subjects ANOVAs will be conducted to assess differences across timepoints. Multivariate logistic and linear regression analysis will be used to identify predictors of adverse outcomes. Anonymised data generated will be made available in an open-access repository.

Study status

Not yet recruiting.

Discussion

To address the increasing prevalence of multimorbidity and the complexities associated with older adult health needs, social care systems internationally recognise the need to shift away from the acute episodic model of care towards a more co-ordinated, planned and integrated model in the community setting. The conventional model of healthcare delivery Is primarily designed to address individual health conditions, which often inadequately address the multifaceted needs of older adults.16 The AFHS 4Ms framework encourages healthcare providers to consider the holistic health and well-being of older adults, facilitating more effective and integrated care. This approach not only enhances quality of life but also mitigates the risk of adverse health outcomes and supports ageing in place.

Dissemination

This study will be submitted for publication in a peer reviewed journal and disseminated in the form of presentations at national and international conferences. Findings will also be presented to residents, family members of residents and staff at Mowlam residential care centres.

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Hayes C, Galvin R, Shortt S et al. Exploring the Age-Friendly Health Systems Framework in Memory Care Centres: A protocol for a mixed-methods study [version 1; peer review: 2 approved with reservations]. HRB Open Res 2026, 9:30 (https://doi.org/10.12688/hrbopenres.14353.1)
NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article.
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Open Peer Review

Current Reviewer Status: ?
Key to Reviewer Statuses VIEW
ApprovedThe paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approvedFundamental flaws in the paper seriously undermine the findings and conclusions
Version 1
VERSION 1
PUBLISHED 06 Apr 2026
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7
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Reviewer Report 04 Jun 2026
Michele Board, Bournemouth University, Bournemouth, England, UK 
Approved with Reservations
VIEWS 7
This has potential to be an interesting study. Having read this I have a few comments for some of the sections as follows.
Setting
Is this across 2 or 3 homes - it says 2 sometimes but lists ... Continue reading
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CITE
HOW TO CITE THIS REPORT
Board M. Reviewer Report For: Exploring the Age-Friendly Health Systems Framework in Memory Care Centres: A protocol for a mixed-methods study [version 1; peer review: 2 approved with reservations]. HRB Open Res 2026, 9:30 (https://doi.org/10.21956/hrbopenres.15809.r55322)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
Views
12
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Reviewer Report 21 May 2026
Victoria Grace Gabb, University of Bristol, Bristol, UK 
Approved with Reservations
VIEWS 12
This article describes a mixed-methods protocol for a study exploring implementation of an Age-Friendly Health System within residential memory care centres in Ireland. The study has two parts: focus groups and qualitative interviews with stakeholders and a prospective cohort study ... Continue reading
CITE
CITE
HOW TO CITE THIS REPORT
Gabb VG. Reviewer Report For: Exploring the Age-Friendly Health Systems Framework in Memory Care Centres: A protocol for a mixed-methods study [version 1; peer review: 2 approved with reservations]. HRB Open Res 2026, 9:30 (https://doi.org/10.21956/hrbopenres.15809.r55315)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.

Comments on this article Comments (0)

Version 1
VERSION 1 PUBLISHED 06 Apr 2026
Comment
Alongside their report, reviewers assign a status to the article:
Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions

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